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Importantly, the sequence region defined as the crotonase domain by a hidden Markov model (HMM) and the region covered by the BLAST alignment are largely overlapping; see Fig. 5D for an illustration of selected alignments used to define edges from the full-length crotonase network.
All the selected alignments (one alignment per read) were used to annotate and quantify splicing events.
Based on sequence identity, we selected alignments of five nearly full-length genome sequences.
The selected alignments were edited and manually refined with the program ED of the MUST package [ 51].
For the selected alignments, all unaligned bases in 3′ ends of local alignments were regarded as non-templated additions.
The ten selected alignments ranged in length from 155 to 648 amino acids and from 14% to 60% missing residues.
Similar(45)
For both simulated data sets, we align these reads using the four selected alignment programs.
For reads that were aligned into multiple locations (LTRs), we considered only one randomly selected alignment location.
The selected alignment methods are analyzed in terms of their computational complexity and the estimates of numbers of arithmetic operations for each method are given.
Allows modeling of the query based on any selected alignment.
The individual blocks within the selected alignment were then mapped to the human genome.
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CEO of Professional Science Editing for Scientists @ prosciediting.com