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We selected a mouse model in which the Mmu16 trisomic region extends beyond the DSCR, as comparative genetic studies [25], [26] have indicated that trisomy for only the DSCR is not sufficient for a complete DS phenotype.
We selected a mouse monoclonal antibody in a human antibody background to estimate non-specific binding by means of aminoacid sequences of the constant regions of mouse IgGs, which differ from corresponding human sequences.
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In the first lab session, the girls observe as a researcher selects a mouse and places it in a machine that is akin to a treadmill with mice.
For assessing IP3R1 haploinsufficiency in particular, as found in SCA15 and SCA16 patients [ 3, 12, 15, 16], it would also be useful to select a mouse model with a large heterozygous deletion mutation in IP3R1.
Select a mouse.
We selected a single mouse leukemia cell line, L1210, in this study and conclusions drawn in this system will need to be validated in other mammalian cells.
To further explore the translational significance of above findings, we selected a PDGCX mouse model (SGC031) harbouring MET amplification and MET overexpression (IHC 3+), but no gene amplification and/or protein overexpression of FGFR2 and HER2.
To evaluate the system, 55 cDNA clones with predominantly unknown function were selected from a mouse testis cDNA-library.
A transposon mutant of the corresponding gene in F. novicida was negatively selected in a mouse model of infection [19].
Mouse Click: a gene can be selected by a mouse click.
Definitions are displayed when any word is selected with a mouse click.
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