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The Dominantly Inherited Alzheimer's Network includes 160 FAD mutation carriers who are cognitively normal, or with very mild memory complaints who will receive gantenerumab, an anti-Aβ antibody, solanezumab, or placebo for 2 years followed by a biomarker study to select the most efficacious drug for a further 3-year trial with a cognitive endpoint.
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The development and clinical implementation of gene signatures that predict response to commonly used chemotherapeutic agents could facilitate selecting the most efficacious therapeutic regimen given the molecular characteristics of an individual's tumor.
Thus, results from an in vitro susceptibility testing are an important tool to guide a veterinarian in selecting the most efficacious antimicrobial agent(s) for therapeutic and prophylactic intervention.
Select the most likely object.
Select the most powerful marketing tactics.
Select the most useful and economical size.
Transplant physicians are frequently faced with the difficult choice of selecting the most appropriate and efficacious option for oral antifungal prophylaxis in alloHCT recipients.
EE and TAM doses were selected based on UWW dose response studies which identified 100 μg/kg as the most efficacious dose for each compound.
Dry nitrogen is the most efficacious atmosphere.
Perhaps the most efficacious miracles are the small ones.
Jack Kemp lauded his former aide: "It will be proven the most efficacious of all the reforms".
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CEO of Professional Science Editing for Scientists @ prosciediting.com