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This allows: (a) to investigate quantitatively the effectiveness of different upgrading criteria, (b) to select rationally intervention hypotheses, both in the retrofitting and rehabilitation of existing hospitals and in the design optimization of new ones, and (c) to evaluate different investment options for seismic vulnerability mitigation.
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The dopant metals were selected rationally by considering the stability of the Ni-based binary alloys.
In combination with additional mutations selected rationally, they produced antibodies that assembled as heterodimers with up to 93% purity.
In five of the six complementarity-determining regions, diversity-carrying residues were selected rationally on the basis of a model structure of FITC8 and on known antibody structure function relationships, resulting in variation of 11 centrally located, cavity-lining residues.
Considering these parameters may not only improve patient stratification for more effective trial design, but may also allow smaller patient cohorts to be studied, if these are selected rationally for therapy according to the status of the drug target or molecular lesion.
What matters for our happiness is whether we select them rationally and, as it turns out, this means selecting them in accordance with the virtuous way of regarding them (and virtuous action itself).
Thus, using EpCAM as a target, we provide evidence that DARPins can be conveniently selected and rationally engineered to high-affinity binders of various formats for tumor targeting.
On the basis of the different coordination nature of lanthanide and transition-metal ions, the multifunctional organic ligands with mixed coordination sites such as isonicotinate have been elaborately selected to rationally construct a series of homochrial and achiral 3D Ln M coordination frameworks built from inorganic heterometallic chains with improved thermal stability.
Thereby, the aim of this paper is (i) to formalize such conflicts, and (ii) to rationally select consensus choice by measuring reputation scores of the wiki users.
It has become impossible to rationally select a reasonable wine at a reasonable price.
The structure-based approaches were implemented to design and rationally select the molecules for synthesis and anti-HCV activity evaluation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com