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Frustration about the pace of change, even disagreement on select issues, of course is understandable.
Disagreements in selected articles were resolved by discussion and consensus.
Any disagreements regarding selected text and creation of codes were discussed and resolved.
Two authors (FB and SC) reviewed the manuscripts and independently selected the eligible manuscripts; disagreements were resolved by discussion.
KN and DG independently reviewed the articles and any disagreements in selecting the studies between them were resolved by discussion.
As pointed out by one of the reviewers, potential disagreements among selected subject experts may occur, which can cause the expert opinion to follow a bimodal (i.e., two groups of experts with opposite views) or even trimodal distribution.
Data were collected by two investigators from the selected studies, with disagreement resolved by consensus.
Inter-rater consistency was calculated using Cohen's Kappa, which ranged from 0.80 to 0.89 for all the four cases across the two physicians; the third physician only reviewed selected cases with disagreement.
The software-generated triage note contains all the call registration data, the complete set of answers to the triage questions, the most urgent disposition, care points selected, and caller disagreement information.
Significantly, here we provide specific mechanistic explanations based on 5′UTR and RBS strength to explain the mRNA-to-protein expression disagreements for a select set of proteins.
The assignments producing the minimum disagreements are then selected.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com