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Exact(17)
Thus, tensile forces determine the first spatial segregation of cells during mammalian development.
Cluster growth curve of simulated segregation of cells without collective motion characterized by exponent value α = 0.33 is shown for reference (black solid line).
In the case of early pregnancy, the segregation of cells undergoing progesterone-induced proliferation from those that express PR implicates a paracrine mode of action for progesterone-induced mammary epithelial proliferation, whereas the preparturient decline of PR expression underscores the need to remove this signal for full functional differentiation of this tissue.
This fact indicates that the segregation of cells with a single TO is favored even in cells with MTOs.
Finally, the segregation of cells in chimera based on the genetic make up suggests that genes encoding specific cell surface molecules are also activated at this time.
Dynamic intercellular adhesion is fundamental both for the recognition and assembly of cells with similar properties and for the segregation of cells into distinct populations [9], [10], [11].
Similar(43)
Performing segregation experiments using cell types with altered myosin activity they have demonstrated that differential actomyosin-dependent cell-cortex tension is required and sufficient to direct the segregation of cell types and determine the final configuration of the segregated domains.
The dual function of theta oscillations is realised as synaptic plasticity and the segregation of cell assemblies in the available phase space [16].
As shown in Figure 5A, differences in gene expression lead to a segregation of cell types and a clustering of samples by cell type when the data from all genes were used.
Segregation of cell populations adopting different cell fates into distinct domains is governed by their mechanical properties and active motion, and constitutes an important driving mechanism of gastrulation and tissue organization.
Three-dimensional segregation of cell populations is most prominent during gastrulation, the early phase of embryonic development resulting in the formation of main germ layers that later on give rise to all tissues.
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