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Although this suggests for aneuploidy, extensive analysis of male meiotic chromosome behavior revealed that pWOX2::CENH3-GFP plants do not show any MI or MII segregation defect and always produce haploid spores (n = 76) (Table 2), indicating that chromosome segregation imbalances do no occur or are extremely rare in diploid meiosis.
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This segregation is needed to avoid dosage imbalances whose effects scale with <ν>.
The use of FISH to confirm deletions and/or duplications detected by microarrays showed that these genomic imbalances resulted from the segregation of a parentally balanced insertion [ 14, 15].
This implies that S should be approximately proportional to the divergence time and independent of <ν>, or S/Ks should remain approximately constant and low relative to the level of segregation experienced by duplications that generate dosage imbalances.
Understanding the origins of these phenotypes is important because this could provide insights into how chromosome mis-segregation and the resulting imbalanced karyotype impacts normal cell physiology and disease states.
Large imbalances were seen in terms of occupational segregation and wage gap.
If regarded it as true that the conservation of Sgo1 across species, mutations in human Sgo1 might induce chromosome-segregation defects in meiosis, which would lead to genetic imbalances.
New York City never saw a lawsuit over school segregation but community leaders "challenged practices and policies that perpetuated racial imbalance and educational inequity across schools".
Meiotic abnormalities can cause unequal segregation of homeologous chromosomes and are a likely driver of the chromosomal imbalance between genomes observed in both Tragopogon allotetraploids.
Demographic segregation?
Tax imbalances?
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