Sentence examples for segregation errors from inspiring English sources
Moreover, meiotic segregation errors can be distinguished from mitotic ones.
Chromosome segregation errors also happen frequently post fertilization in mammalian preimplantation embryos.
In addition to cancer cells, human oocytes are particularly prone to chromosome segregation errors during meiosis (Hassold and Hunt, 2001).
To study the effect of artificial oocyte activation (AOA) on chromosome segregation errors in the meiotic divisions.
Mitotic segregation errors strongly influences copy number, while structural aberrations can occur at unstable genomic regions, or through aberrant DNA repair or methylation.
A recent study by Crasta et al. (2012) showed that in HeLa cells, micronuclei generated due to mitotic chromosome segregation errors, contained whole chromosomes that had persistent albeit aberrant DNA replication (Crasta et al., 2012).
These data strongly suggest that Separase deregulation may cause chromosome segregation errors during gamatogenesis.
Therefore, during gametogenesis, chromosome segregation errors come not only from meiosis but also from mitosis.
Yet, the molecular mechanisms underlying chromosome segregation errors remain unclear due to the lack of appropriate model systems [10].
Our present study provides the first evidence that PGCs undergo mitotic chromosome segregation errors at the beginning of gametogenesis.
Inefficient activation of Mps1 results in weakened mitotic checkpoint activity and the persistence of falsely attached chromosomes, causing frequent but non-lethal chromosome segregation errors [16].
