Segregation analyses by using an F2 population derived from a cross between the soil-surface rooting mutant and wild-type Nipponbare indicated that the trait was controlled by a single recessive gene, designated as sor1.
The parameter estimates and test statistics from the complex segregation analyses are presented in Table 3.
To account for proband ascertainment, ascertainment correction was applied in all segregation analyses by conditioning each pedigree's likelihood on the affection status of the proband.
Findings from segregation analyses are often used to formulate tailored research hypotheses on the disease under investigation, and/or to decide on the type of investigative effort on the disease.
These studies ranged from genetic epidemiological and segregation analyses [8], [14] that investigate mutations in specific genes by molecular genetics [10], [11], [13], [17], to risk and survival analyses [5], [12], [18] among families and pedigrees with affected relatives.
We conducted familial correlation, commingling, and complex segregation analyses of 224 families from the Chaoshan population and 403 families from the Taihang population using the FPMM program of S.A.G.E.
Using the Statistical Analysis for Genetic Epidemiology program, we carried out complex segregation analyses of ovarian cancer affection status by fitting different genetic hypothesis-based regressive multivariate logistic models.
However, segregation analyses showed differing inheritance modes in these breeds.
Segregation analyses indicated single-locus insertions for both lines.
The POE segregation analyses were performed assuming no residual polygenic background.
The segregation analyses suggested a recessive autosomal inheritance with almost complete penetrance [ 113].
