The 2×2 factorial design enabled us to segregate the effects of the GR mutation that are potentially generalizable across strains from strain-related differences as well as interactions of GR genotype and strain.
See related research by Pandharipande et al., http://ccforum.com/content/14/2/R38 and related commentary by Kress, http://ccforum.com/content/14/3/164 Dr Pandharipande and colleagues should be commended for segregating the effect of dexmedetomidine, an alpha-2 adrenoceptor agonist, in sepsis [ 1].
In the interest of completely segregating the effects of the lesson plan from the effects of lecture-based instruction in evolution, we chose to use an online posttest.
We demonstrated that in the RGxBB segregating population, the effect of the year, the environment and its interaction with the genotype were highly significant.
To circumvent this problem, one could potentially use time-staggered treatments to temporally segregate the cytotoxic effects of individual agents, but precise pharmacokinetic and pharmacodynamic measurements will be of paramount importance for the proper implementation of this approach.
Following this, in the section "Cluster identification using phenotypes from control and multiple compounds", the ability of the proposed method to automatically segregate phenotypes arising from the effect of different compounds is analyzed.
This small effect of marker density on accuracy indicates that other factors are also important, such as differences in segregating QTL or in the effect of QTL across populations due to differences in genetic background between populations [ 7, 8].
"If Northerners oppose school desegregation or the integration of the suburbs with affordable housing, that's not considered racism, though it has the effect of segregating blacks that is at least as damaging as it was in the South".
Additionally, dementia has the effect of segregating caregivers from others because of the care needs and problem behaviors of dementia sufferers.
