The 2×2 factorial design enabled us to segregate the effects of the GR mutation that are potentially generalizable across strains from strain-related differences as well as interactions of GR genotype and strain.
See related research by Pandharipande et al., http://ccforum.com/content/14/2/R38 and related commentary by Kress, http://ccforum.com/content/14/3/164 Dr Pandharipande and colleagues should be commended for segregating the effect of dexmedetomidine, an alpha-2 adrenoceptor agonist, in sepsis [ 1].
In the interest of completely segregating the effects of the lesson plan from the effects of lecture-based instruction in evolution, we chose to use an online posttest.
To circumvent this problem, one could potentially use time-staggered treatments to temporally segregate the cytotoxic effects of individual agents, but precise pharmacokinetic and pharmacodynamic measurements will be of paramount importance for the proper implementation of this approach.
Twin heritability and linkage studies segregate the genetic and environmental effects based on the assumption that monozygotic twins are genetically identical, and so their phenotypic differences are of environmental origin.
We demonstrated that in the RGxBB segregating population, the effect of the year, the environment and its interaction with the genotype were highly significant.
Should there be any doubt as to the sinister aims of these organizations, consider the case of Wake County, NC, where a local AFP affiliate commandeered the school board in 2009 and immediately effected policies to re-segregate the school system.
The lack of a segregating main effect on the X-chromosome was surprising, as this chromosome has been generally shown to play a major role in the evolution of hybrid male sterility [14].
But as depicted in this figure, the impact of genomic GC-bias on the amino acid usage is so strong that the organisms under study have been segregated, in effect, on the basis of their average genomic GC-content.
