Suggestions(5)
Exact(8)
We wanted to know which was the most likely segmentation in two segments of the alignment according to site likelihoods for all topologies.
Alleles from each gene were extracted and concatenated for each genome, the panel of concatenated sequences was aligned by using ClustalW software (31 ), and the core segments of the alignment were used for construction of a neighbor-joining phylogenetic tree by using MEGA software.
Segments of the alignment were assigned to structural motifs based on the KcsA structure.
To identify individual putative breakpoints in each recombinant sequence we used a sliding-window, bootscanning approach, which computes a bootstrapped maximum-likelihood phylogenetic tree for overlapping segments of the alignment (in our case, each 20 nucleotides) [52].
In an alignment of such genomes, historical recombination events define segments of the alignment with separate ancestral relationship.
Core segments of the alignment that are shared among all isolates included in the analysis were identified and concatenated.
Similar(52)
To add further complexity, current implementation of sequence search algorithms do not consciously differentiate between the 3D-structural sequence segments and the non-globular segments of the alignments.
Instead, by re-evaluating the fold-critical segments of the alignments through score dissection, dissectHMMER exhibits a deeper search depth and maintains a correct search path to elucidate more fold-related and relevant domain hits.
An ungapped segment of the alignment was selected to be the artificially misaligned segment.
Each sequence appears in at most one segment of the alignment.
Once this maximum is found, it clearly associates a most likely topology to each segment of the alignment.
More suggestions(2)
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com