If there are gaps between the membranes, the algorithm will present the gaps as "holes" in the cell cluster, and segments of "cell junctions" within the "holes" are treated the very same way as junctions that are outside the tight cluster mask (see supplement for definition).
Assuming that in the resulting 2D array the parameter d corresponds to the horizontal dimension and p to the vertical one, an image line segment only contributes to a vertical segment of cells in the corresponding orientation plane of the Hough space, since the value of the parameter d remains constant for all the points on the line.
In situ hybridization analysis revealed abundant sigma receptor 1 expression in ganglion cells, cells of the inner nuclear layer, inner segments of photoreceptor cells and retinal pigment epithelial (RPE) cells.
Immunohistochemical studies localized AAV-CBA-GDNF-derived recombinant protein to cell bodies, inner segments, and outer segments of photoreceptor cells as well as to retinal pigment epithelial cells.
In control animals, these subunits colocalized in the large majority of GABAergic synapses in the ML, and clearly outlined the cell body and major dendritic segments of Purkinje cells (Fig. 1A1,B1).
Axo-axonic (chandelier) cells (AACs) make synaptic contacts exclusively on the axon initial segments of principal cells (Somogyi, 1977; Somogyi et al., 1983).
Chandelier (or axo-axonic) cells are a distinct group of GABAergic interneurons that innervate the axon initial segments of pyramidal cells and are thus thought to have an important role in controlling the activity of cortical circuits.
In our analysis, we correlated the absolute value of a cell-cell force vector that is transmitted through a small segment of the cell-cell interface with the E-cadherin-GFP intensity of that interface segment.
At higher magnification (Fig. 4B), VEGF was seen to be primarily localized to the region of the outer segments of photoreceptor cells.
Our model incorporates four semi-Markovian states with attached occupancy distributions to model the four types of segments of epidermal cells between lateral organs and two Markovian states to model the occurrence of either primordia or emerged roots in the proximal and distal zones.
