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Agilent's ADM-2 algorithm was used to identify chromosomal segments of altered copy number in individual subpopulations from all tumors.
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This broader distribution of the diameters and the higher values of the irregularities observed in different vascular segments may be because of altered blood flow and to the high pressure of the tumour stroma.
Tumours within the simple-profile subgroup appear similar to the BRCA1 and BRCA2 subgroups in terms of altered segment lengths but differ in that they display considerably less complex genomes.
Among the segments studied, colon had the greatest number of altered immune response transcripts and the highest magnitude of change.
Identification of segments carrying altered numbers of copies was achieved with the Patchwork R package (Mayrhofer et al., 2013), which quantifies the log-relative change in DNA content for each chromosomal region.
These tests, however, do not capture the existence of altered mobility at a single segment or unique patterns of aberrant segmental mobility.
The possibility of altered kinematics is important as this may also affect the kinetics and hence musculoskeletal demands on the trunk segments.
Then, the pitch of these two short segments is altered using the PSOLA technique [22], which will result in two signals having exactly the same pitch.
Larger reaches were characterized by increased involvement of leg and trunk body segments, altered inter-segmental coordination, and decreased inter-segmental movement time lag.
It is expected to increase the diversity and complexity of transcriptomes and proteomes through chimeric sequence segments or altered regulation.
The boundaries of the segment with altered phylogeny reside at the ends of MAT1-1-3 and MAT1-1-1 genes for MAT1 idiomorph and MAT1-2-1 and MAT1-2-5 for MAT2 idiomorph, so that flanking regions have canonical phylogenetic configuration.
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