The argument continues that the classic patterns of the disease described above exist only to assist clinicians superficially, and the true hetergenous nature of the disease should be seen as a complex interplay between environmental factors, genetics, and resultant differences in pathophysiology.
As demonstrated by recent studies (e.g., [ 23, 24]), configurational analyses can be particularly attractive for public health researchers when health outcomes are seen to be the result of a complex interplay of causal and contextual conditions.
Taubes is critical of scientists' tendency to see disorders as "multifactorial" and "multidimensional"—that is, as arising from a complex interplay of factors.
The placement of recombination events is a complex interplay between various genomic features (e.g., see Pan et al., 2011).
Current data relay (chronic) inflammation and cancer, through a complex interplay of autocrine and/or paracrine interactions of signaling molecules (see [ 5], for a recent discussion).
See related review by Sutherland and Walley, Resistance to infection and its outcomes are influenced by a complex interplay between the host, the microbe, and the environment.
Self-renewal of mouse ESCs is dependent on the intracellular pathways involving a complex interplay between specific epigenetic processes, miRNAs and transcription factors, such as Oct4, Nanog or Sox2 (see for reviews).
In conclusion, we have demonstrated a complex interplay of biological, spatial and temporal factors on body size that collectively explained between 60 and 84% of the variation seen in Alberta's grizzly bears.
Like other addictions, gambling addiction is the consequence of a complex interplay between an individual and a product.
The discrepancy between democratic India and authoritarian China is due to a complex interplay of political, geographical, and economic factors.
