Based on the outcomes of previous studies, it seemed rationale to test the combination of Caelyx with infusional 5-FU, FA and MMC with the aim of identifying a regimen to deliver 5-FU, MMC and doxorubicin in their presumably most effective manner: infusional 5-FU modulated by sodium FA (mixed in one pump), dose-dense MMC and liposomal pegylated doxorubicin.
Such a step seems both rationale and empirically effective; however, it questions the role of the end-user platform.
Until all three are given equal consideration, there seems little rationale for implying that Aβ is more potent than the other two.
However, there seems little rationale for the apparent variation in NHS policy on how many and which people are permitted to accompany a woman in an ambulance.
Given the substantial antitumour activity of BRAF inhibitors such as vemurafenib in BRAF-mutant disease, there seems little rationale for pursuing the combination of sorafenib and dacarbazine in that setting; the antitumour activity of sorafenib detected in this study could be further explored in patients without activating BRAF mutations.
If AD is a primary amyloidosis, as is postulated by the amyloid cascade hypothesis, then reducing Aβ would seem a rationale way to proceed with drug development.
I know he was shot in the head, but the rationale is what bothers me the most, Colonel, and the rationale seems to be that by releasing this photo, we will incite people that already hate us – and we put a bullet in the guy's brain.
The rationale seems to be: case closed, why bother investigating anything?
Without anality and sexual dysfunction, the rationale seems to be, how could you make them credible?
Security is inevitably invoked, but the security rationale seems to have been upended by the Web.
