The mean differences (80% confidence intervals) from placebo in WOMAC pain score were 0.04 (−0.63 to 0.71) for PF-04457845 and −1.13 (−1.79 to −0.47) for naproxen, indicating that whilst naproxen seemed efficacious, PF-04457845 was not differentiated from placebo.
Inodilator therapy with milrinone seems more efficacious in attaining sustained hemodynamic improvement than does pure intravenous vasodilator therapy with nitroglycerin in treating patients with decompensated heart failure.
This preventive policy seems partially efficacious on early manifestations of allergy but does not restrain the allergic march, especially in its respiratory manifestations.
Indium seems more efficacious to detect perivalvular complications than valvular surface infections, but its time-consuming images' acquisition limits its utilization.
In patients with low-risk eRA, MTX with step-down glucocorticoid bridging seems more efficacious than MTX step-up monotherapy, with a comparable number of AEs observed over the first 16 treatment weeks.
Feinberg was by turns gentle and hostile, confiding and withholding, depending on what seemed most efficacious.
Site specific adhesion barriers seem most efficacious against adhesion (re)formation as they remain on the exact place of application during mesothelial healing.
Venlafaxine seem more efficacious both in reduction of symptoms and in term of number of responders (the corresponding odds ratio is 2.01) for a similar safety profile.
Indeed, if a significant aspect of inflammation in atherosclerosis is driven by IL-1α, the effects in CANTOS may not seem as efficacious as required, or at worse the trial may fail losing a real therapeutic opportunity.
Though very high doses were used in Group 2 (ivermectin injections followed by oral administration), the protocol seemed less efficacious compared to ivermectin injections (Group 1) and selamectin spot on (Group 3), respectively, although not statistically significant.
It seems to be efficacious to blend the results of a variety of algorithms that approach the problem from different perspectives.
