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Twenty or 30 years ago, it seemed reasonable to predict that men and women were becoming more alike as traditional gender career pathways merged.
Based on primary sequence alone, it seemed reasonable to predict that the PIKKs were either lipid kinases or dual lipid protein kinases, but the evidence that PIKKs transmit signals exclusively through the phosphorylation of protein substrate is increasing rapidly.
Since GSK-3 inhibition efficiently suppresses NF-κB in pancreatic cancer cells, and downregulates NF-κB targets associated with chemotherapy resistance such as XIAP and Bcl-XL, it seemed reasonable to predict that this would also sensitize these cells to gemcitabine.
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While speculative, it seems reasonable to predict that cytokines that are most prominently attenuated by both indomethacin and rosiglitazone may be relevant to the allo-specific impairment in neuron production or survival.
Given that the concept of added value is to assess the contribution of the school environment to students' achievement, it seems reasonable to predict that indices of added value will show more shared environmental influence than raw measures of achievement, and that genetic influences will be reduced.
Secondly, it seems reasonable to predict that the ratio of the different transcripts reflects the levels needed to produce the optimal ratio of proteins for each capsid.
The examinations also each have knowledge and clinical assessments, and it seems reasonable to predict that there will be some congruence on those assessments.
Notwithstanding the absence of previous references, it seems reasonable to predict that an examiner without medical education and practice will experience even greater difficulties in performing a standardized technique of manual fixation than an examiner with such skills.
However, considering only NSCLC with AC histology, the level of CD44v6 expression had no significant association with lymph node metastases or tumor stage in the study by Ramasami et al. [ 20] Thus, it seems reasonable to predict that tumor invasion and metastasis could be enhanced by the cell-ECM interaction in CD44-overexpressed tissue or by cell-cell interaction in CD44-deficient tissue.
It seems reasonable to predict that there are both susceptibility and regulatory factors, such as fetal polymorphisms of Fc receptors and cytokines, each of which could influence the extent of the proposed pathologic cascade to result in permanent third-degree heart block.
And her request seemed reasonable to me.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com