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Every year, Natural England is besieged by people seeking licences to kill legally protected wildlife.
It is seeking licences to prospect in more than 1.2m hectares (3m acres) in the area.
Members of the Association of Medical Research charities last year called on the Government to intervene by assuming responsibility for seeking licences in the event of new evidence of a drug's benefit for a new group of patients.
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None of the 23 firms who have sought licences to operate in the special economic zone has yet been granted one.
And more historic progress has been made this week as the UK's fertility regulator gave the green light for clinics to seek licences to create embryos with the DNA of three people, an experimental technique developed to help women with mitochondrial mutations have healthy babies.
A change in the law backed by medical charities and the Royal College of Physicians would require the Health Secretary to take on responsibility for seeking new licences for existing 'off-patent' drugs, when they are found to have benefits against other diseases.
The Lynx UK Trust is seeking a licence for trial releases in Scotland and the Kielder forest in Northumberland.
Shell has won approval to export the stuff; ConocoPhillips is seeking a licence and BHP Billiton, a mining company, has sold at least two cargoes.
All operators seeking a licence under the 2005 Gambling Act must apply to the Gambling Commission next month, before a new regulatory regime comes into force in September.
Anyone seeking a licence will have to go on a training course and prove they understand laws on privacy, bribery and data protection and will be vetted to see if they have a criminal record.
Among other things, it is trying to become a "Facebank" that offers services such as electronic money and international payments: it was reported this week that the firm was seeking a licence for such activities in Ireland.Shares in some Asian web companies, such as Tencent of China, have fallen, too.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com