Sentence examples for seed rules from inspiring English sources

Efforts to strike a balance between these narratives have often played out in passionate discourses surrounding seed rules and regulations.

But Philippe Baret, a genetics professor at the same university, says the proposed seed rules may hamper agricultural approaches such as organic farming or agro-ecology.

tRF-5s and tRF-3s also match clusters observed in PAR-CLIP data with canonical seed rules, indicating that AGO-tRF complexes are able to associate with RNAs.

We find that tRF-5s and tRF-3s, but not tRF-1s, are very abundant in AGO1, 3 and 4 photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) data and use canonical miRNA seed rules to associate with mRNAs.

The rules are generated as part of each release which ensures their evolution along with the UniProtKB with little or no manual intervention while also providing seed rules for exploitation in the UniRule system.

19– 23 Subsequent biochemical and structural findings provided a better understanding of the seed rule in molecular terms.

17 The seed rule states that perfect and contiguous pairing to the 5′ region of the miRNA nucleotides 2 8, called the seed region, is crucial for the specificity of target selection (Fig. 1A).

The seed region of miR-141 differs to that of miR-200c by one nucleotide at position 4 of the miRNA; therefore, miR-141 and miR-200c have, based on the "seed" rule, different computationally predicted targets.

39, 46, 70, 71 Interestingly, Ago-binding sidentifiedified by HITS-CLIP are more often located in ORFs and violate the seed rule more frequently than previously expected, although it is unclear what fraction of these sites represent authentic target sites.

35 However, more difficult to elaborate are an increasing number of experimentally identified target sites that neither obey the seed rule nor have a pairing scheme specific enough to be generalized into defined site types (Figs. 1F and 1G).

41, 53 Aiming to examine the general applicability of the seed rule, one study established a sensor system based on the C. elegans neuronal miRNA, lsy-6, and tested 14 predicted targets containing perfect seed matches to lsy-6 in their 3′ UTRs.