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First, we do not see PN inhibition onto iNC cells as a major assumption in the paper, and we were not dealing with this question at all in the text.
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However, by comparing these histograms, we can see that PN odor responses are slightly clustered around the weak end of the PNs' dynamic range at peak i.
Therefore, figures based on surveys conducted by the OECD are better able to demonstrate the scale of the problem (see Junankar PN Raja 2011).
To assess the efficacy of polypectomy, one can calculate one minus the ratio of 5- or 10-year probabilities of malignant transformation rate after polypectomy (PT) to the corresponding transition probabilities pertaining to the disease natural history (PN), see Appendix A (Treatment efficacy=1− PT/ PN).
From Figure 3, it is seen that Pn increases only slowly with the increase of U0 while Td increases significantly with the increase of U0.
A correlation was also seen between pN staging and higher rates of adjuvant chemotherapy prescription.
The maximum pulling forces for the ATP-channel are between 737 1080 pN, and averaged at 816 pN (see Figure 4C).
For example, the two red traces in Figure 1E show ∼5-nm transitions at ∼5 pN, which match well with the transition between (SSB 56 and (SSB 35 modes observed in constant force experiment at 5 pN (see Figure 2B-C, 3A: blue and green data points at 5 pN).
Fi for mutant constructs (Fi,mutant) was set to 0 pN (see text).
We performed these experiments and the results showed that there is no obvious internalization of BCRs in case of each of these three NP-TGT sensors (12, 43 and 56 pN, see Figure 2 figure supplement 2A-C).
Consequently, we had to relax the complex to observe NTD refolding at a lower force (1-8 pN, see Figure 2 figure supplement 3, 5 7 and Figure in (Gao et al., 2012)).
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