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This study was designed to compare the successful sedation rate of intranasal dexmedetomidine with and without buccal midazolam on children with autism.
In the DEX group, well-controlled sedation rate was higher (p = 0.002) and delirium rate was lower (p = 0.03) during ventilation compared with those in the non-DEX group.
The sedation rate plummeted.
If one examines MRI of all body parts, the sedation rate is approximately 4%.
To prove a reduced sedation rate in comparison with conventional colonoscopy would require a truly comparative, preferentially randomized, and blinded study; the results of this pilot study may be used as hypothesis generating for such a study.
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In the first two experiments, rats were evaluated on a sedation rating scale, and ataxia/motor incoordination was assessed using the rotarod apparatus.
The ratings remained different from placebo for up to 3 h, but were no longer statistically significantly different, primarily due to progressively increased sedation rating in the placebo condition.
To investigate plasma drug concentrations and the effect of MK-467 (L-659′066) on sedation, heart rate and gut motility in horses sedated with intravenous (IV) detomidine.
The investigated parameters were respiration, sedation, recovery rate, side effects, time to discharge, and patient satisfaction.
To study the effects of MK-467, a peripheral α2-adrenoceptor antagonist, on sedation, heart rate and blood pressure after intramuscular (IM) coadministration with 25 μg kg−1 of dexmedetomidine in cats.
To determine the effects of brimonidine tartrate ophthalmic solution on sedation, heart rate (HR), respiratory frequency (fR), rectal temperature (RT) and noninvasive mean arterial pressure (MAP) in healthy cats.
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