Your English writing platform
Discover LudwigExact(60)
- BIS-Index® and Entropy® values in sedated volunteers are not determined by sedation levels.
The large intra-individual and inter-individual variability of BIS® and Entropy® values in sedated volunteers makes the determination of sedation levels by processed electroencephalogram (EEG) variables impossible.
It remains unknown, however, whether loss and return of response to the ARM occur at similar sedation levels.
So now some I.C.U.'s are trying what seems like a radical solution: reducing sedation levels and getting patients up and walking even though they are gravely ill, complete with feeding tubes, intravenous lines and tethers to ventilators.
We focus most of this discussion on the problem of controlling sedation levels during surgical procedures; results from the application of linear parameter varying and robust L1-adaptive modeling and control approaches are presented in some detail.
The study was designed to answer the question in the 'real world', with minimum patient exclusion criteria, do nurses and doctors rate ICU patient's sedation levels using the SAS similarly?
We hypothesized that loss and return of response to the ARM occur at similar sedation levels in individual subjects, independent of the propofol effect titration scheme.Twenty-one healthy volunteers aged 20-45 yr underwent propofol sedation using an effect-site target-controlled infusion system and two different dosing protocol schemes.
Loss and return of ARM response occurred at similar sedation levels in individual subjects.Reproducible ARM dynamics in individual subjects compares favorably with clinical and electroencephalogram sedation end points and suggests that the ARM could be used as an independent instrumental guide of drug effect during propofol-only sedation.
Pa and Nb latencies showed the best correlation with sedation levels (0.685 and 0.658, respectively).
It has been thought that deeper sedation levels were associated with higher levels of comfort.
First, it has shown that lighter sedation levels are feasible and safe even in a lower nursing staff ICU.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com