Future trials should be prospectively registered, have secure allocation concealment, adequate sample sizes and should be reported according to established standards.
We planned to include in the initial analysis, trials that met the following criteria: calcium supplementation without any co-supplements; random allocation with secure allocation concealment; and double blinding with placebo.
Prior to enrollment, using blind and secure allocation by computer, the study team randomly assigns participants to one study arm using a random number generator: CKD-ATSM or usual care.
Using blind and secure allocation by computer, we will randomly assign participants to one of three intervention arms: 1) control group ("Usual Care study arm"); 2) TALK SWI ("TALKS Program study arm"); and 3) TALK SWI plus the Live Donor Financial Assistance Intervention ("TALKS Plus Program study arm").
Using blind and secure allocation by computer, we randomly assign participants to one of three intervention arms: 1) control group ("Usual Care", N=70); 2) the informational intervention ("PREPARED", N=70); and 3) the informational plus the financial assistance interventions ("PREPARED plus Financial Assistance", N=70).
Using blind and secure allocation by computer, we randomly assign participants to one of three intervention arms: 1) control group ("Usual Care"); 2) video and booklet intervention only ("TALK Program"); and 3) video, booklet plus social worker intervention ("TALK Plus Program").
Because segregation prevented blacks from attending graduate school in the state, Chandler secured an allocation of $5,000 annually to help blacks attend out-of-state graduate schools.
Hence they now underline the need to standardise care and secure fair allocation of resources.
To secure concealed allocation, central telephone randomisation at the Clinical Research Centre, University Hospital of North Norway was used.
Randomisation will be undertaken using web or telephone access to a secure remote allocation system, with allocation made at the level of the individual, minimising by PCT, gender, patient age group and presenting complaint.
Vaccine security requires the guaranteed production of vaccines, secures multi-year allocations for vaccine financing, the development of long-term forecasting of vaccine requirements and helps reduce wastage.
