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If the switch loops are open, corresponding to kinesin's detached ADP states, the switch II loop and the P-loop can interact closely with each other, which would secure the closed conformation of the nucleotide cleft.
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The use of Arg298 as a molecular latch to secure the barrel in this closed state is beautiful in its simplicity.
Fifty years ago, civil rights organizations, pushed by young Student Nonviolent Coordinating Committee (SNCC) organizers, came together to form COFO, the Council of Federated Organizations, in order to work together more effectively to secure the vote in Mississippi's closed society.
McCollum and Reid faced the prospect of a maximum 15-year prison term but struck a behind-closed-doors plea bargain to secure the shorter sentence.
Authorities mobilized the army, closed roads, and surrounded the square hoping to secure the money and capture the criminals.
Secure the underlayment.
Secure the Straws.
Secure the property.
Secure the cables.
Secure the braid.
Secure the skis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com