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Double focusing sector instruments also enhance the information afforded by "metastable" ions, allowing identification of precursor and product ions.
The first generation of magnetic sector instruments in the 1940 s are often named "Nier spectrometer" after its inventor Alfred Nier [19], cf. Fig. 1.
In periods of acute crisis, health security teams could generate proposals for how the ISF could stem the loss of health sector instruments of governance like health records and epidemiologic surveillance systems.
The first ion mobility mass spectrometers coupled with magnetic sector instruments were also built in the 1960s [ 2], almost immediately after the development of the first ion mobility spectrometers.
In the past, double-focusing magnetic sector instruments had a leading role in this area, but nowadays the abovementioned mass analyzers offer clear advantages, such as more favorable price, smaller size and easier operation.
Since then the combination of ion mobility cells with both continuous and pulsed ion sources has been solved and ion mobility spectrometers have been coupled with many different kinds of mass analysers, including time-of-flight (TOF) analysers [ 3, 4] magnetic sector instruments [ 2], quadrupoles [ 5, 6] ion traps [ 7– 9] and Fourier transform ion cyclotron resonance instruments [ 10– 10].
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The mass spectrometer is a miniature magnetic sector instrument controlled by microprocessor-driven power supplies.
Three different types of ICP-MS instrument, a quadrupole, a single collector magnetic sector, and a multicollector magnetic sector instrument, were compared by Diemer et al. [ 70].
They used a magnetic sector instrument equipped with a MALDI ion source and they coupled a drift-time ion mobility spectrometer after it.
Whilst the existence of a public sector instrument for performance appraisal is undoubtedly positive, its implementation appears to be challenging and it likely that it will take time for its use to become established [ 20].
Those terms – officially the "ODA modernisation of private-sector instruments implementation details" – are now being discussed in greater detail at high-level meetings this week in Paris.
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