In the case of single-gene Mendelian inheritance, the disease may be passed on as an autosomal recessive, autosomal dominant, or sex-linked recessive trait, as discussed in the section Classes of genetic diseases.
Hence, this paper focuses on austenitic stainless steel (European grade 1.4301 also known as 304) beam-columns composed of square hollow sections (SHS) and circular hollow sections (CHS), considering different cross-sections classes (1 to 4), according to Eurocode 3 (Eclassificationtion.
The depth-to-thickness (D/t) ratios of the outer tubes were varied such that all cross-section classes were considered.
This is reflected in the European guidance for structural fire design EN1993-1-2 [1], which specifies different effective yield strengths for different cross-section classes.
According to this new methodology, an effective cross-section is calculated for Class 3 and Class 4 cross-sections and the yield strength at 2% total strain is used for Class 4 cross-sections as recommended by Eurocode 3 for the other section classes.
The resulting strain-based formulations avoid the use of section classes for fire design, and take into consideration the plastification effects, plastic stress distribution, and strain-dependent non-linear material behaviour of steel at high temperatures.
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Moreover, the effects of strain hardening and section class may conveniently be included in modelling.
The behaviour of laterally restrained steel beam-columns with slender cross-sections (Class 4) where local buckling occurs under fire situation is numerically investigated.
