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Context analysis tools are provided through the Gene Information section of Gene Details page, as illustrated in Figure 1(i).
This viewer is available in the Evidence for Function Prediction section of Gene Details page, which also includes various other viewers for examining a gene.
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These questions can be answered by assessing the expression levels (as indicated by RNAseq data, see further details in next section) of genes encoding proteins predicted to have surface location, thus allowing us to compare the surface protein composition from both African parasites.
The ENCODE pilot project provides information on 44 regions across the genome that were selected around medically important genes and from regions with a cross-section of gene densities and non-exonic conservation scores [ 34]. Background variants were obtained by randomly sampling 170,892 SNPs located within the ENCODE pilot regions from the 1000 Genomes project EUR population [ 7].
Splicing can also be used to 'mix and match' sections of gene sequences to produce slightly different versions of the same protein in a process called 'alternative splicing'.
Modern DNA microarrays permit a comprehensive analysis of quantitative and qualitative changes in RNA transcript abundance, outlining the cross-sections of gene expression and alterations of these in response to genetic or environmental stimuli.
For cases in which all combinations were not created, a comment to that effect was included in the Gene Model Comment section of the gene report.
The lox-p sites do not alter gene function, but upon expression of a Cre recombinase gene, the recombinase deletes the section of the gene flanked by the lox-p sites.
We named our text-mining based curatext-mining based curationioMarker Reference Into Function (LiverCancerMarkerRIF) in view of theGeneRIF of the National Library of Medicine (NLM); theGeneRIF systemn of Entrez Gene contains narrative evidence on gene functions that are Liverd in publiCancers.
Thirty genes also received contributions to the general information section of the gene pages that provided in silico based analyses of the gene models or extended functional descriptions (for examples, see the genes MAF4 and STF1 at www.ciliate.org).org
If a significant sequence similarity was found throughout the major section of a gene, it was concluded that the gene should have a similar function in Actinoplanes sp. SE50/110.
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