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Secondly, collection of patient-level cost data during follow-up is a resource intensive exercise.
Secondly, collection of tissue samples in post-mortem requires consideration of several novel factors not relevant when examining other tissue types – such as cause of death, post-mortem RNA integrity and post-mortem interval [ 20].
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Secondly, data collection and storage are more decentralized to cope with the large quantity.
Secondly, data collection for both the development and validation studies was conducted at the same hospital site.
Secondly, since collection of prostate tissue requires a surgical procedure, which would only be undertaken in subjects with evidence of symptoms of prostate enlargement.
Secondly, sample collection was determined by the attending clinicians rather than by strict criteria and were not taken from consecutive patients as some clinicians may have taken blood cultures without filling out the necessary data collection form.
Secondly, the collection of mitochondria themselves may produce a local exaggeration of oxidative stress via the overproduction of superoxide by the electron transport chain in the mitochondria, leading to a self-propagating pathway of neuritic dystrophy [ 18, 59].
Secondly, data collection depended on the capacity of the data collector to read, understand and collect the right information, indicating that there might have been few issues of data quality.
Secondly, the collection of these data in a central national database is done primarily for reimbursement purposes and therefore should not be biased by the pursuit of pharmacoepidemiological studies.
In particular, comparing the results obtained through DEA models based on different hypotheses concerning returns to scale, in the first place it is verified whether a particular municipal dimension emerges as an efficient benchmark, and secondly if waste collection is organized above or below its optimal scale in the municipalities taken into consideration.
Secondly, our data collection procedure is simplified.
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CEO of Professional Science Editing for Scientists @ prosciediting.com