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Prophylaxis, whether primary or secondary, was defined as regular factor replacement for at least 46 weeks per year 6.
Infertility (primary or secondary) was defined by the couple not being able to conceive after one year of regular, contraceptive-free intercourse.
Resistance in new cases (primary) was defined as in vitro resistance in patients who did not have a history of anti-TB treatment, while retreatment resistance (secondary) was defined as in vitro resistance in patients previously treated with any anti-TB medication.
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Any patient with a 7-day secondary hospitalization or 30-day secondary death was defined as experiencing an "outpatient failure".
Conversely, the secondary lesion was defined as "independent" when it presented different morphological and molecular profiles from the primary lesion.
The secondary endpoint was defined as the influence of IAP and ACS on the outcome.
To deal with this problem, a secondary goal was defined in Stage 2 of the method.
Secondary bacteremia was defined as a bloodstream infection that develops as a result of a documented infection with the same microorganism at another body site.
Secondary CS was defined as a CS performed after the onset of labor.
The secondary outcome was defined as safety and dropout rate.
An agreed set of goals (one primary and up to three secondary goals) was defined.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com