Sentence examples for secondary repression from inspiring English sources
However, our analysis did not reveal a bona fide repressor that is downregulated by MeCP2 and that can potentially cause a secondary repression in Mecp2-null mice and a secondary activation in MECP2-Tg mice.
It may be that desmosome dissolution occurs simply as a secondary consequence of repression of E-cadherin.
It is possible that this difference arises because the secondary pathway, Xist repression linked to the pluripotency program [ 18], plays a more dominant role in the ΔCpG XY ES cell line.
Strikingly, for either mark, an exceedingly small subset of marked genes is perturbed upon loss of respective enzyme, suggesting either existence of multiple redundant silencing mechanisms or these methylation events being a secondary consequence of repression.
The effect on Cdc25A expression may be secondary to the repression by TGF-β of c- myc, because in some cell types Cdc25A is induced by c- myc [ 70].
Previous work reported that excess nitrogen sources had been implicated in the repression of secondary metabolism such as penicillin biosynthesis in Penicillium sp. (Sanchez et al. [1981]).
Most of the time, secondary metabolites have a catabolic repression effect.
This single amino acid mutation highlights the key role of the secondary pocket of CRYs for repression.
In addition, the secondary effect of miR-182 repression resulting in upregulation of E-cadherin through CBX7, which we have shown, may have important implications in reversing epithelial neoplasias to a more normal state.
Indeed, it has recently been reported that short RNAs (50 200 nt), transcribed from repressed loci by stalled RNA polymerase II, interact with the PRC2 complex through their stem loop secondary structure and mediate gene repression through epigenetic modification [ 41].
This study also demonstrated that the complex media were superior to the semi-synthetic media in avoiding the negative effect of catabolite repression on production of secondary metabolite.
