Sentence examples for secondary progression from inspiring English sources
After an uncertain period of time, many RRMS patients change into secondary progression with or without superimposed relapses (SPMS, secondary progressive MS).
Increasing evidence indicates that the postischemic inflammatory response might play a detrimental role in the secondary progression of stroke injury [2].
The olfactory brain volumes in MS patients with primary and secondary progression were significantly smaller than those of MS patients with relapsing-remitting progression.
We also analysed 4 studies reporting risk of secondary progression in MS and found that this fell just short of statistical significance with considerable heterogeneity (RR 1.88, 95% CI 0.98 3.61, p = 0.06).
Secondarily we aimed to establish any correlation between both smoking and latitude and between smoking and the risk of secondary progression in MS. We searched OLDMEDLINE and MEDLINE from 1960 to May 2010 with the phrase: "(smok* OR cigarett*) AND (multiple sclerosis OR ms)".
The first analysis included only patients having entered secondary progression.
In contrast, Year 3-secondary progression relapses were inversely and significantly related to risk of entering the secondary progressive phase, being nearly half in those with 5 attacks (HR = 0.45) versus those with a single attack (HR = 0.85) during the Year 3-secondary progressive period (Table 4).
Frequent Year 3-secondary progression relapses predicted modestly longer times to onset of the progressive phase while other variables more strongly predicted shorter times based on more frequent relapses (Table 3).
The risk of accumulating severe disability decreased proportionately to relapses experienced in Year 3-secondary progression.
> -wrap-foot> The relationships among relapses in Years 1 and 2 and Year 3-secondary progression and the first inter-attack interval in Table 3 highlight Year 3-secondary progression as the outlier.
The attainment of endpoints from onset of the progressive phase was significantly affected by prior early relapses and not by relapse frequency in Year 3-secondary progression.
