Isn't it curious, though, that chemotherapy often accelerates aging, causes sleeplessness and depression, promotes fatigue and anxiety, lowers blood counts, causes the onset of menopause and requires powerful secondary medications to deal with its side effects?
Evidence has been recently found in favour of persistent somatosensory system central sensitization in chronic headache secondary to medication overuse (medication overuse headache, MOH) by recording cortical somatosensory evoked potentials (SSEPs) [10, 18].
Any indicator of patient adherence to secondary prevention medications, for example, self-reported medication adherence or medication persistence, medication possession, individual patient data on prescriptions, pharmacy claims, electronic monitoring and drug tracers in the blood or urine.
Despite improvements in the use of secondary prevention medication, there is further scope for achieving more from these medications[ 18].
Since proportions taking both aspirin and lipid-lowering medications did not change, there is little evidence to suggest that an overall reduction in adherence to secondary prevention medication was seen in the sample.
Hering-Hanit et al. [13] studied 26 adolescents with chronic daily headache secondary to medication overuse.
In 31% of all participants, imaging revealed findings that led to further exams or a therapeutic intervention, e.g., starting a secondary preventive medication.
On-treatment ALT flares are considered to be either from disease activity or secondary to medication.
Pharmacogenetic studies aim to identify genetic variations associated with drug treatment response or adverse effects secondary to medication [ 16, 17].
