It leads to hemorrhage, edema and secondary inflammatory infiltration of the pulmonary interstitium and alveoli [16].
Osteoarthritis (OA) in the TMJ is characterized by deterioration of articular cartilage and secondary inflammatory changes.
Potentially, the pneumococcal capsules only elicit a severe secondary inflammatory response in patients genetically prone to be pro-inflammatory.
Lipopolysaccharide and other bacterial products stimulate the immune cells of the host to elicit secondary inflammatory mediators, including cytokines.
A fundamental issue is whether such variation is a primary cause for disease or reflects secondary inflammatory change.
Tissue damage, secondary to these mechanical injuries, results in a secondary inflammatory injury known as biotrauma [35], which exacerbates the primary mechanical injury.
CD8α+ T cells could be released into the circulation, which could, in turn, contribute to the secondary inflammatory cascade in the brain to induce more severe damage.
Following the formation of necrotic myocardium, a secondary inflammatory immune response occurs as myofibroblasts are recruited to the area resulting in scar formation and reduced ventricular function [3].
However, foreign particles' presence within inflamed tissue may affect the drug release or targeting, and/or cause a secondary inflammatory reaction.
However, it is conceivable that immunosuppressive drugs might affect secondary inflammatory events triggered by glomerular immune deposits or even proteinuria per se.
Immune response cells, predominantly local microglia, marcophages and lymphocytes, are involved in the degenerative processes and elicit a secondary inflammatory reaction, which sets the pace of progressive neuronal damage.
