Sentence examples for secondary hit from inspiring English sources

The biggest problem last season was a rash of injuries: Ravens starters missed a total of 77 games, with the secondary hit particularly hard.

Specifically, the study indicated that suspected loss of consciousness, motor incoordination or balance problems, being in a fight, having an initial hit from another player's shoulder, and having a secondary hit on the ice were all associated with increased risk of subsequent concussion diagnosis.

A compound was considered a secondary hit if it produced a significant increase in lifespan at two consecutive concentrations.

In line with a lack of impact on tumor latency, loss of Raidd did not release the pressure to inactivate p53, a known secondary hit, usually observed in about 25% of all Eμ- Myc lymphomas.

Hence, it remains possible that the phenomenon of reduced p53 activation in the absence of Caspase-2 is cell type-specific, for example, in lung epithelium, and/or a particular secondary hit, or a fully transformed cellular state.

BrdU incorporation analyses showed that only four out of the selected nine compounds repressed cell proliferation at > 50% as compared with DMSO-treated control cells (Fig 1C and D), yielding a secondary hit rate of ˜ 0.4%.

Indeed, several genes involved in syndromic and monogenic forms of migraine have been defined, allowing a significant contribution to the mechanisms generating the attacks, but the timing and specific contribution of secondary hits remain largely unclear.

To obtain initial mechanistic insights we next sought to place secondary hits in the context of two major components of insulin signaling, FOXO1A and AKT.

It is postulated that extrinsic stresses (either environmental or therapy-induced) play a major role in promoting secondary "hits" that can lead to higher cancer predisposition [33], [34].

A more in-depth look at the mode of encounter for these residues shows that for both D54 and E65 the main cause for the reduction in total binding time is a significant reduction in secondary hits.

To rule out the possibility of secondary hits accumulated during double balancing and multiple crosses influencing phenotypes, we chose strongest shg and arm alleles (shg2, shgE17B and arm2) double balanced with Dcas1 (shg2/CyO;Dcas1/TM6B,y+x,shgE17B/CyOCyO; Dcas1/TM6B,y+x,arm2/FM7i-GFP,BP,B; Dcas1/TM6B,AntHu,y+) and crossed to Df 3L Exel6083/TM6B,Ubx,y+.