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During the same year, Baade first proposed the use of the Type Ia supernova as a secondary distance indicator.
The results are then averaged to obtain a weighted distance measure for each pair of units (secondary distance).
We observed no heterogeneity in the ORs between NPP sites, sexes, age group, and calendar time periods in the primary distance measure, nor generally in the secondary distance measures.
None of the ORs differed significantly from unity, and adjustment for the covariates did not affect the ORs for primary distance measure (average distance) or secondary distance measures (distance at index date and minimum distance).
We used this average distance (in meters) as the primary distance measure, and the distance at the index date and the minimum distance (i.e., shortest distance from any of the subject's residences to the NPP) as secondary distance measures.
We calculated the secondary distance tree of the network using the program UVCLUSTER (Arnau et al. 2005) and then we used the program TreeTracker (Marco and Marín 2007) to compare the hierarchical representation of the interactome with the dichotomic partition (duplicate or nonduplicate) of the mitochondrial gene set.
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Finally, a dendrogram is obtained from the matrix of secondary distances.
The other two, RCluster and SCluster, provide alternative ways to obtain the matrices of secondary distances from a graph.
After creating the matrix of secondary distances, the program uses the phylogenetic algorithm(s) chosen to build a dendrogram.
To calculate the matrix of secondary distances, the algorithm saves, for each pair of nodes, the number of iterations in which they have been clustered separately, and the secondary distances between each two units are calculated by dividing those values by the number of iterations.
A second significant advantage of Jerarca is that it also includes two novel algorithms, RCluster and SCluster, which provide alternative ways of computing the secondary distances between the nodes of the graph.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com