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As an alternative hypothesis it has been proposed that decreased HBV replication by limiting HSP60 release from infected hepatocytes, results in a secondary decrease in the frequency of CD4 T cells with regulatory/suppressor capacity (Tregs).
Although the exact underlying mechanisms remain unclear, the proliferation, apoptosis, and invasion of MMH-RT and HCC cells could be regulated by both blockade of aPKC ι signal pathway and the secondary decrease in aPKC ι.
Immediately upon standing, the reduction in blood pressure is accompanied by (1) an initial increase in peripheral vascular resistance, either as part of baroreflex-mediated sympathetic activation or secondary to passive changes in vessel calibre, and (2) a secondary decrease in resistance approximately 10 s after the initial onset of hypotension (Olufsen et al. 2002).
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These responses are often characterized by primary decreases in important indices of cardiac and thermoregulatory function, along with secondary decreases in associated parameters.
As λ i / σ i increases (requiring more neurons in each module), these secondary peaks decrease in amplitude.
In contrast, PETCO2 did not detect the secondary slow decrease in VCO2,br back to baseline because PETCO2 measures neither exhaled volume nor the shape of the PCO2 waveform.
We cannot deny that more prompt administration of systemic medications might have reduced the complications such as secondary cataract, decrease in corneal endothelial cell count, iris atrophy, and corneal opacity.
Profound changes in gene expression were seen with both aromatase inhibitors, including many classical estrogen-dependent genes such as TFF1, CCND1, PDZK1 and AGR2, but also many other genes that are likely to represent secondary responses; decrease in the expression of proliferation-related genes were particularly prominent.
This is an intuitively understandable result because as ρ increases, the average number of available channels for both new and (inter- and intra-) handed off secondary sessions decreases in detrimental of system capacity.
Our observed reduction in home-indoor PM2.5 levels could have been secondary to decreases in home-outdoor PM2.5 levels.
Between D28 and D56 the number of secondary septa decreased in hyperoxic mice (P < 0.05) and stayed at the same level in normoxic mice.
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