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Secondary data will be matched to individuals to allow consideration of external factors, such as local labour market conditions.
Secondary data will be collected from national registries to obtain information on the use of health services and mortality.
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Non-compliant data (secondary evaluation data) will be stored as accession-referenced files.
All primary and secondary outcome data will be completed online and thus will be automatically entered into a database.
Secondary outcome data will be obtained through the Clinic Characterization Form, Patient Tracking Form, In-Clinic Patient Survey, Post-Study Follow-Up Patient Survey, and Family Physician Survey.
Baseline differences in demographic as well as the primary and secondary outcomes data will be analysed using two-sample t-tests for parametric and Wilcoxon test for non-parametric distribution as well as Chi-Square test for nominal data.
Primary and secondary outcome data will be collected at baseline and at six weeks and six months after the time of treatment onset (surgery for the surgery group and time of enrolment for the nonsurgical group).
Secondary endpoint data will be compared between the two arms in the ESRD group (active vs placebo) and between the two active liraglutide groups (type 2 diabetes with ESRD vs type 2 diabetes with normal kidney function).
The collector of the secondary patient outcome data will be blinded to the randomisation schedule.
To address our final secondary objective, qualitative (interview) data will be analyzed concurrently with quantitative and qualitative data collection.
A secondary analysis of the data will be performed to examine other important variables that impact asthma outcomes.
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