Sentence examples for secondary annotation from inspiring English sources
4. By primary and secondary annotation. 5.
We have previously shown that for analysis of M.tuberculosis H37Rv proteins, the Tuberculist annotation performed better than a posterior annotation provided by the TIGR Institute (not used in this work), but some peptides only entered in the secondary annotation were also found (de Souza et al., 2008).
An analysis of the DE transcripts was performed using only the top DE transcripts with annotation derived from primary annotation sources rather than passaged secondary annotations (Table 3).
They are called primary annotations and can be combined in the Web interface to obtain, for example, secondary annotations representing regions of the globe by making a logical 'OR' of several countries.
For all the genes contained in Sanger-MGP, we then generated a list of secondary phenotype annotation predictions by going through all the existing phenotype annotations for a gene and adding those phenotypes that have been mapped based on co-occurrence.
MicroRNA secondary structure annotation was taken from mirBase [ 22].
Genes with a secondary metabolism annotation term were also down-regulated in overrepresented manner after manipulation, when compared to expression during biting.
Applying the method described by Oti et al. first to the primary phenotype annotations only, and then to both primary and predicted secondary phenotype annotations, shows that the biological coherence of clusters increases when adding the predicted secondary phenotype annotations.
Furthermore, even though the annotations have been validated using the predicted secondary phenotype annotations in PhenoDigm's disease prediction algorithm, the disease gene candidate predictions based on the secondary phenotype data are not yet available.
We further extracted the secondary structure annotations for all residues in the current dataset using the DSSP program [38] and calculated their distributions as displayed in Figure 2, according to three secondary structures: α-helix (H), β-strand (E) and coil (C) [39].
If the secondary phenotype annotations improve the phenotypic overlap of genes and diseases, the ROC curves used for the evaluation should show an improvement.
