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Furthermore, it was deemed that there would be a smaller proportion of pathological X-rays in the databases, compared to MRI that are performed as a second line imaging modality to confirm knee disorders.
Therefore, CBCT should be considered as a second line imaging modality in assessing complex anatomical sites with multiple overlapping bones, such as the wrist (Fig. 5) and foot, in case of negative CR but with high clinical suspicion of a fracture.
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Depending on the symptoms, conventional x-rays are the first line imaging modality for the evaluation of wrist pain.
MRI should not be used as a first line imaging modality, because deposits appear as vague regions of low signal on T1 and T2, and can be missed.
As shown in Fig. 3, bone SPECT/CT should not be the first line imaging modality, but only after conventional radiographs, detailed history and thorough clinical examination fail to produce a diagnosis (Hirschmann et al. 2013).
While bone scintigraphy reliably allows the distinction of cellulitis from osteomyelitis, it is rarely used as the first line imaging modality in the emergency setting owing to the unavailability of radioisotopes at night, prolonged scan time and poor soft tissue delineation.
While CT is the first line imaging tool, other imaging modalities may provide additional valuable structural or functional information.
Standard echocardiography is the first line imaging exam to differentiate athlete's heart RV remodeling from pathological conditions.
CT and MRI are typically the first line imaging modalities of choice in the evaluation of most patients with suspected pNETS.
Ultrasound (US) has been regarded as the first line imaging modality for detection of FLL, whereas it is difficult for baseline US to distinguish between them because ICC has no specific features [ 2, 3, 8– 10].
Quickly, it became evident that this method provided the highest sensitivity for the detection of breast cancer and bMRI has been established as a major second-line imaging tool [3, 4, 5, 6, 7, 8].
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