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Six Indian states Chhattisgarh, Maharashtra, West Bengal, Andhra Pradesh, Tamil Nadu, and Gujarat were selected based on two state-level indicator criteria: first, the average population per branch of formal financial institution as of the end of June 2009, and second, incidences of indebtedness of rural households.
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This rose steadily to 90% for first incidence screening and to 94.5% for second incidence screening (fig 2).
The corresponding values for a first incidence screen were 1.7%and90%0% and for a second incidence screen were 1.1%and94.5%5%.
Of these invitations, 307 235 were first incidence screens on a first invitation, 123 142 were first incidence screens on a second invitation, and 214 985 were second incidence screens on a first invitation.
The uptake of the first incidence screening on a first invitation was 54%, first incidence screening on the second invited was 86%, and second incidence screening on a first invitation was 46% (fig 1).
The proportion of cancers at stage I dropped from 46.5% for prevalence screening to 41% for first incidence screening and 35% for second incidence screening.
Results Of 510 990 screening episodes in all three rounds, 248 998 (48.7%) were for prevalence, 163 483 (32.0%) were for first incidence, and 98 509 (19.3%) were for second incidence.
By the third round, there was a complex mix of prevalence screens from first, second, and third invitations; first incidence screens from first and second invitations; and second incidence screens from a first invitation (box).
The uptake of first incidence screening on a first invitation was 54% and on a second invitation was 86% and on a first invitation for second incidence screening was 46%.
In addition, we have found that both first and second incidence screening are associated with significant yields of neoplasia and that the positive predictive value for cancer does not drop between first and second incidence screening.
Although the positive predictive value for both cancer and adenomas fell between the prevalence screen and the first incidence screen, they did not fall between the first and second incidence screens.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com