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A 32-year-old female with type 1 diabetes mellitus, who was one of two kidney/pancreas recipients, had a duodenal perforation during her second dosing cycle, which led to loss of her pancreas graft and withdrawal from the trial.
Nevertheless, for patients who respond poorly to the first injection, a second dosing may still be safely performed.
A second dosing was performed after 2 days (T = 2).
A second dosing schedule was evaluated in this study.
Endometriosis was surgically induced during the week of the second dosing.
No change was observed from first to second dosing cycle (Fig. 2b).
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It should be noted that the second dosing-to-first dosing analysis excluded subjects who did not receive or did not complete the second PA dosing due to the occurrence of liver function abnormalities fitting the nonredosing criteria.
Then she took the second dose.
Now I can expect a second dose at Fourteenth Street.
He died only after a second dose was administered.
Some states, including Massachusetts and New Hampshire, require students to receive a second dose before entering college.
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