Sentence examples for second complementarity from inspiring English sources

The highly hydrophobic cleft is bordered on one side by the negatively charged second complementarity determining region (CDR2) and the unusually long positively charged CDR3 of the heavy chain and, on the other side, by the CDR1 of the light chain.

Second, complementarity is less cost effective in general.

Furthermore, γ4λhuCD152 binds specifically, with nanomolar affinity, to an extracellular constituency encompassing the putative second complementarity determining region (CDR2) of CD152, whereby it can react to activated CD3+ cells.

Dihedral angle values comparison of the first and the second complementarity-determining region (CDR) of M12-VH domain with an average values show a significant deviation; therefore, M12-VH domain structure indicates either the existence of a new canonical subclass or a link among the subclasses of canonical main-chain conformation in VH3 family.

Clone11 phage had mutations in the first and second complementarity-determining region (CDR1 and CDR2, respectively) of the light chain (Q27R and V56A, respectively).

Despite great differences in overall size and structure, the DR5-binding peptides and antibodies shared a tripeptide motif, which was conserved within a disulfide-constrained loop of the peptides and the third complementarity determining region of the antibody heavy chains.

However, a detailed analysis reveals significant constraints in the sequence and amino acid composition of the third complementarity region of the H chain (CDR-H3), which lies at the center of the antigen binding site.

Although the diversity of the obtained repertoire was maintained mainly by the third complementarity determining region of the heavy chain (CDR-H3), their changes in the near UV circular dichroism resulting from NP-binding allowed for classification into three groups according to the same rules applied in the pathway classification of the maturated Abs.

This method subdivides the bulk T cell population into 180 "groups" defined upon i) the rearranged variable ß (Vß) gene segment used, and ii) the length of the T cell receptor (TCR) third complementarity determining region (CDR3).

Interestingly, the third complementarity determining region of the heavy chain (CDRH3) of 7C8 comprises 13 amino acid residues while the majority of CDRH3 domains from murine IgG1 are only 8 to 9 residues long [30], [31], [32].

They all originate in the relatively common IGHV5-51 H chain V gene 37, but vary in terms of length of the rearrangement encoding the third complementarity determining region of the H chain (CDRH3) 12-199 codons).