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Indeed, so much so that some other potentially first class candidates, including current Vice-President Joe Biden, may decide not to even enter the race.
Now, however, they could make such a statement only if they were willfully ignorant of the dozen or more first-class candidates who are available.
First, relaxing the candidate-mutation filters to include second-class candidates did not identify any additional mutations (Table 2).
To define the second-class candidates, we relaxed the parameters for DFNY1-66 candidate SNP calling to include uniqueness less than 5 and coverage more than 1×.
"There's always a chance because we've got a first-class candidate, it's an open contest and we're fighting for every vote," he said.
Twelve out of 18 (67%) first-class candidate mutations were confirmed in the cell-line DNA, and 0/5 (0%) second-class candidate mutations were confirmed.
The second class of candidate distributions, i.e., conventional distributions, includes five conventional pdfs: multivariate Laplace (MLD), multivariate Gaussian (MGD), and three multivariate Gaussian Laplace mixtures (MGLD).
Finally, JAFFA flags a fourth class of candidates 'Potential Regular Transcript', which appear to be novel transcripts between adjacent genes [ 28].
We argue that, given the large amount of predictions that fall in the first class, predictions from the second class should be considered as promising candidates for further studies.
These first two categories speak for themselves, though it's worth noting that (prior to his very public wooing by the establishment Goldsmith) a poet like Steve Roggenbuck seemed a particularly likely candidate for this second class of author.
Among oomycete species, many non-N-R class candidates were found in the first round of HMM searches, while few non-N-R class candidates were found in non-oomycete species.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com