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The first categorisation divides the images into two classes, which are no diabetic retinopathy and diabetic retinopathy, while the second categorisation consists of four stages, involving no diabetic retinopathy stage, non-proliferative diabetic retinopathy (mild, moderate and severe cases), proliferative diabetic retinopathy and advanced diabetic eye disease.
Second, categorisation of the features among the RMIC integrated care domains was assessed in a second international Delphi study.
Cut off values for SCC to determine subclinical mastitis have been a subject of debate [ 41], therefore in this study a second categorisation level for SCC was used based on suggestions of Schwarz et al. and Berglund et al. [ 42, 43] (healthy samples- SCC <100,000 cells/ml; SM samples -SCC 101,000 200,000 cells/ml; clinical mastitis (CM) samples-SCC >200,000 cells/ml).
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Finally, the third categorisation is the one that contains the ten retinopathy stages.
A second experienced researcher not involved in the study checked all transcripts for accuracy of comments, right quantity of approbations and first categorisation.
The credibility of the study is good because of the relatively large sample of participants as well as a skilled investigator with sound experience in focus group methods, and support by a second investigator who analysed the transcripts for accuracy of comments and the first categorisation.
With respect to mortality, using the first categorisation explained in Materials and Methods (biomarker 'higher than' or 'equal to or lesser than' the upper limit of normality), no significant differences were obtained in the Kaplan Meier curves plotting survival time (data not shown).
Categorising height by quintiles instead of the first chosen categorisation gave an RR of 1.20 (95% CI: 1.16 1.25) when comparing the highest with the lowest quintile.
Third, this categorisation is not necessarily exhaustive.
Other activities, such as cleaning, cooking, and domestic work were grouped together as a first line of categorisation (see Table 1).
Third, the broad categorisation into indoor, built outdoor, and natural environments ignored the qualitative differences within the environments in the same category.
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