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Rule of searching level (RSL): RSL searches all attributes that depend functionally and directly on the given level and that respect the level conformity constraint.
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These adaptations involve searching individual level hospital claims data for codes corresponding to the Charlson index categories.
MP trees were searched using the Tree-Bisection-Reconnection (TBR) search option with the initial trees setting at 50, MP search level setting at 5, and maximum number of trees setting at 2000.
If more than one search level are used (hierarchical search), the optimization of Grid resources' allocation relies on the distinction between computationally demanding, high-accuracy and less demanding, low-accuracy evaluation tools.
The search follows a Hierarchical and Distributed scheme (HDMAEA), with more than one search level, each of which is associated with a different problem-specific evaluation tool and a different number of semi-isolated demes.
MP trees were obtained using the Close-Neighbour-Interchange algorithm [77] with search level 3 [76], in which initial trees were obtained by random addition of sequences (10 replicates).
The MP tree of amino acid sequences was obtained using the Close-Neighbor-Interchange algorithm with search level 3 in which the initial trees were obtained with the random addition of sequences (10 replicates).
The MP trees were constructed using the close neighbor interchange (CNI) method with search level 1.
The close-neighbour-interchange algorithm was chosen with a search level of three.
The ME tree was searched for using the close-neighbor-interchange (CNI) algorithm [ 42] at the search level of 1.
Tree searching used the Close-Neighbor-Interchange method with 1000 initial random trees and a MP search level of three.
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