Hand searching journals, and checking of reference lists of retrieved papers increases retrieval of relevant papers.
In addition, participants were identified through contact with ministries of health, academic institutions, professional networks, announcements at conferences, and searching journals to identify authors with relevant expertise.
Two further publications were added after hand searching journals and reference lists of papers, with one additional unpublished manuscript being supplied by the manufacturer.
Pearling (checking the reference lists of identified studies) and hand searching (journals predating electronic databases or not appearing in electronic databases) were also conducted to increase the search base.
A database of published and unpublished literature will be assembled from searches using a comprehensive search strategy, examination of reference lists in systematic reviews, hand searching journals and contact with experts in the area.
Systematic reviews of the literature were conducted using various electronic searches (MEDLINE, EMBASE), government reports, and hand searching journals and reference lists on the following topics: MCADD screening tests, diagnosis, outcome, treatment, effectiveness, cost, and cost-effectiveness.
