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The search for valid bioisosteric replacements is an ongoing challenge in the discovery of sEHI.
For TNCCR, Algorithm 2 is applied to search for valid combinations.
Then, with as the new start, the process continues to search other valid, and will end after the searching.
This article uses hindsight to describe some of the potential pitfalls that hinder the search for valid disease resistance genes.
The latter predicts which solutions are expected to cause the simulation to fail, and its prediction is incorporated with the model prediction to bias the search towards valid solutions, namely, for which the simulation is expected to succeed.
We also conducted a systematic search for valid events that were not reported by participants.
The search for valid and reliable biological and clinical markers to predict responsiveness to a particular targeted therapy and optimize treatment success for a particular individual must continue.
The use of a structured RQ has been proposed as a systematic way to construct the study question to aid the search for valid answers [ 22].
Reliable outcome prediction for DFS and overall survival (OS), however, still remains difficult, even for patients with similar clinico-pathological characteristics, and the search for valid clinical and/or molecular markers for prognosis and prediction of therapeutic response is ongoing.
Such research should continue to search for valid biomarkers of endocrine dysfunction and at the same time include the existing measurements as described above, to facilitate comparability between study groups.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com