Your English writing platform
Discover LudwigExact(10)
When applied in the context of shape similarity searching, these filters can significantly improve throughput performance by avoiding expensive superposition optimization computation of conformer pairs that cannot possibly meet a pre-defined shape similarity search threshold.
The false negative rate can be estimated from (i) the mass accuracy and (ii) the search threshold.
On the other hand, the frequency of false positives depends on the "density" of the database (the number of molecular formulae within a specific nominal mass window), in addition to the mass accuracy and search threshold.
All but four are truncated elements, i.e., they are solo-LTRs or fragments with a length shorter than our search threshold.
The search threshold for accepting each individual spectrum was set to the default value, with a false-positive value of 4%.
Therefore, using the same BLASTN search threshold levels as were used in this study, a significant increase in the number of LUGs with homology to wheat ESTs is not likely to be observed in the future.
Similar(50)
As shown in Table 2, AR-0.73 consistently produced ~20% fewer hits than ROCS on average, when using identical shape Tanimoto search thresholds.
The trends were independent of both the target database and the search thresholds.
Narrower search thresholds (Δthres = 1 or 1.5 σ) did not result in substantial improvements in annotation quality, as demonstrated by the LC-Q-TOF/MS data (Table 1).
Following generation of phytochemical-like molecular formulae from KNApSAcK via random selection of a derivatization method, simulated m/z values were searched against the KNApSAcK and PubChem databases, employing accuracies of mass analysis and search thresholds corresponding to FT-MS (σ = 1 Da and Δthres = 2 Da) and TOF-MS (σ = 5 Da and Δthres = 10 Da).
The branching-ratio parameters were obtained for each molecular formula database for various experimental errors of mass analysis and searching thresholds (Δthres) listed in Table S1.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com