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The most feasible way to approach this challenge in an unbiased way, which does not require prior knowledge of all on- and off-target interactions of drugs, is to collect systematic measurements across different drugs, cell types and diseases and search for response patterns correlating with the characteristics of the drugs.
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Mr. Putin's letter to Mr. Bush, the Kremlin said, "confirmed his readiness to work towards broadening interaction between Russia and the United States, and for a joint search for responses to 21st-century challenges both to Russia and to the international community".
The somatosensory cortex was localized physiologically with microelectrode penetrations in surgery under barbiturate anesthesia to localize cutaneous somatosensory digit responses in the central sulcus, with the search for responses initiated at +6 mm anterior, and 24 mm lateral.
We searched for response regulator domains occurring in non two-component systems (sequence composition, prosite motifs).
Dutch parents with one or more children aged 0 4 years received an online questionnaire (N = 4000) measuring psychosocial determinants of information-seeking behaviour and self-reports of types and sources of vaccine information searched for (response rate 14.8%).
The search for early response and predictive biomarkers of tumor response to anti-angiogenic agents has so far not provided definitive candidates.
This means to search for high response at peak, low delay to peak, but also a low response at steady-state (see Section "Objective function" and Figure 3A).
Ever since, we have been treated to the sight of Tory message-panic as they search for a response.
"Even better than I expected!" I swallow as I search for a response.
However, molecular changes precede tumour shrinkage, and therefore, there is an increased interest in functional imaging in the search for early response evaluation attributes [2, 3].
In RA, previous studies using blood mononuclear cell isolates and microarray technology have been performed in the search for a response predictor to anti-TNF therapy [30], [31], [32].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com